Équipements à l'ISIS

Instruments available at the Organic and Bioorganic Laboratory

Contact : Nicolas Winssinger

Lyophilisateur (Labcono: http://www.labconco.com/_Scripts/EditC25.asp?catid=242)
Appareil de synthèse parallèle (Argonaut Quest 210 http://www.argotech.com/products/other_products/quest/quest.html)
Centrifuge (4 x 250 mL, 9500 G)
HPLC (Agilent 1100)
Micro-onde mono mode (CEM discovery http://www.cemsynthesis.com/html/dis_page.htm)

Contact : Paolo Samori or Thomas Ebbesen

Fully equipped Digital Instruments - Dimension 3100 Scanning Force Microscopy and Scanning Tunneling Microscopy, running on a Nanoscope IV control unit. This instrument is equipped with the latest optional (“Nanoman”), combined with Dimensional Closed Loop SPM Microscope Head, which allows to manipulate objects in the nanoscale using the SPM tip.
A FEI Dual Beam 235: FIB-SEM-STEM with an ion beam (FIB, ( 5 nm) and electron beam (SEM, (1 nm) which allows state-of-the-art nanofabrication of samples (characterisation, deposition, milling, etc.).
Keithley 6517 A Electrometer / High Res. Meter: (resolution 0.1 femtoAmp) interfaced with a PC
Spin coater with temperature controlled heating stage
Oven for performing thermal annealing in controlled atmospheres
Inverted Nikon and Mitutoyo optical microscope, with liquid nitrogen cooled CCD 2D detector and spectrograph for optical measurements of nanoscopic objects.
Autolab Galvanostat/Potentiostat for electrochemistry work
Spex Fluorolog spectrofluorimeter and Shimadzu UV-VIS spectrophotometer
A class 1000 clean room is available for the sample preparation.
Emitech sputterer, etc.

Contact : Martin Karplus

Contact : Jean-Louis Schmitt

UV-Visible Spectrometer VARIAN CARY3, working also in variable temperature (-10°C à +100°C)
Luminescence Spectrometer SLM AMICO BOWMAN series 2, working also in variable temperature
Büchi Melting point B-540
Microscope Opronic
NMR Bruker AVANCE 400 MHz, with a BBO probe, observable species 1H, 13C, Ag at 31P

Contact : Christian Rick

Cell sorter (Daco Cytomation, MoFlo)
Inverted microscope (Zeiss, Axiovert 200)
High speed camera (Phantom v4.2)
Mask aligner (Suss, MJB-3)
UV lamp (Dymax, 5000-PC avec cabine d'exposition et rideau électrique d'occultation)
Spin coater (Laurell Technologies, WS-400B-6NPP-Lite Single Wafer Spin Processor)
Oxygen plasma chamber (GaLa Instrumente, PlasmaPrep2)

Contact : Burkhard Bechinger (Solid-State NMR Spectroscopy of Membrane Polypeptides)

Bruker Avance 400 wide-bore NMR spectrometer with high power linear amplifiers (3 channels)
Bruker Avance 500 wide-bore NMR spectrometer with high power linear amplifiers (3 channels)
Bruker MSL 300 wide-bore NMR spectrometer with high power amplifiers (2 channels)
several commercial and home-built probes for solution and solid-state NMR spectroscopy (wide line and MAS)
Hewlett Packard vectorial network analyser, 300 kHz to 1.3 GHz
Silicon Graphics Indigo 2 solid impact/R10000, Indigo 2X, O2 and Indy workstations for NMR data analysis
Waters HPLC 600 with columns for preparative and analytical polypeptide purification
Bischoff HPLC with automatic sample injector and columns for preparative and analytical polypeptide purification
Millipore automatic peptide synthesiser
Molecular Biology laboratory
Laboratory for protein purification including low pressure chromatography, preparative isoelectric focusing, preparative and analytical gel electrophoresis, centrifugation, double-beam UV-VIS spectral photometer Uvicon 922, French press, autoclave, etc.
5 Liter fermenter (credits available)